A high-fat, high-sugar diet damages the liver in the long term. Scientists at the German Cancer Research Center (DKFZ) have now identified a characteristic change in the molecular signaling pathways of liver cells in mice that were exposed to such a diet for weeks. It fuels the division activity of hepatocytes and correlates with the risk of patients suffering liver failure after liver surgery.

Immatics N.V. (NASDAQ: IMTX, “Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell-redirecting cancer immunotherapies, announced today the pricing of an underwritten public offering of 15,925,000 ordinary shares at a public offering price of $11.00 per share.

Artificial intelligence (AI) can help dermatologists to detect skin cancer. However, many dermatologists distrust the algorithms' decisions, which they cannot comprehend. Scientists at the German Cancer Research Center have now developed an AI-based support system for skin cancer diagnostics that explains its decisions.

Researchers at the Faculty of Medicine of the University of Freiburg discover key factor in the development of immune cells. New approaches for the treatment of ALPS.

Health Data Futures project - 11/01/2024

Creating a network of trust

In the three-nation project "Health Data Futures", stakeholders and experts from Germany, France and Switzerland have launched a series of patient-centred innovations. Using various future scenarios, the project partners may be able to come up with even more scenarios.

The family-owned MedTech company KARL STORZ announces the acquisition of the innovative software manufacturer Innersight Labs Ltd. (ISL) headquartered in London. In addition to state-of-the-art endoscopes, high-end medical devices, and integrated solutions for the operating room, KARL STORZ is also continuing to expand in innovative software solutions.

Certain brain tumors in small children contain cells that develop very similarly to normal brain cells and others that have already developed malignantly, depending on where they are located within the tumor.

More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers from the Medical Faculty at the University of Freiburg has developed an active substance that might in future represent a new treatment option.

University of Tübingen neuroscientists discover new functions of head-direction cells suggesting they may contribute to episodic memory formation.

Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart’s ability to pump blood in the long term. In a current study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis.

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the Weizmann Institute in Israel and at the German Cancer Research Center (DKFZ) have now shown that p53-mutated mouse breast cancer cells reprogram fat cells.

ProGrün project - 30/12/2023

Using proteins extracted from grassland cuttings to produce animal feed and exploit by-product streams

Animal feed often contains protein from soy and importing it causes major environmental harm. In the ProGrün project, researchers at the University of Hohenheim, including a work group led by Prof. Dr. Andrea Kruse, are developing a scalable technological process to extract proteins from grassland cuttings and use them to make sustainable animal feed produced in the region where it will be used.

Alternative construction materials: mycelium-based materials - 20/12/2023

Using fungi to create sustainable and economical mycelium-based materials

Most of us see fungi as just food - and possibly pathogens. This is a mistake, because these amazing organisms are capable of much more: they grow on plant residues of all kinds, forming a dense and interconnected structure as they spread. The resulting material can be moulded into desired shapes and be turned into new sustainable and economically attractive products such as leather and polystyrene substitutes or building materials.

Facade greening with precipitation retention - 19/12/2023

Rain-retaining living walls improve the urban climate and protect against flooding

Due to dense urbanisation and associated soil sealing, heat and heavy rainfall are becoming an increasing problem for people living in cities. Researchers at the German Institutes of Textile and Fibre Research (DITF) in Denkendorf have developed innovative living walls that not only help cool the environment, but also provide flood protection thanks to their water retention properties.

For the first time, the active substance epifadin has been isolated at the University of Tübingen – Epifadin is produced by specific bacteria in the nose and on the skin of humans, has an antibiotic effect, and is the first example of a previously unknown antimicrobial compound class.

Sustainable binder alternative - 18/12/2023

Copied from insects: new biological wood binder under development

Plastic is all around us; and unfortunately, it is not going away any time soon. The search for more sustainable solutions is fully underway. However, binders that degrade only with difficulty or not at all are still used to bond natural materials such as wood and straw - not yet truly environmentally friendly. Fraunhofer researchers are working on an insect-inspired wood binder that makes bonded wood products both resistant and biodegradable.

All-enzyme hydrogels in action - 13/12/2023

Biocatalytic foams enable the sustainable synthesis of complex molecules

Conventional chemical synthesis processes consume large amounts of energy and environmentally harmful solvents. Prof. Dr. Christof Niemeyer’s team at the Karlsruhe Institute of Technology has generated porous, solid foams from crosslinked enzymes that allow the production of high-quality compounds under significantly more environmentally friendly conditions. The novel biocatalysts are also extremely resistant and have a long shelf life.

The German Cancer Society has certified the Center for Personalized Medicine (ZPM) at Heidelberg University Hospital. At the ZPM Heidelberg, patients with advanced and rare cancers and, in future, people with severe chronic inflammatory diseases will receive a molecular genetic analysis. The detailed information can open up new treatment options for those affected.

Professor Dr. Rohini Kuner from the Medical Faculty of Heidelberg University receives the Leibniz Prize of the German Research Foundation (DFG).

urban BioEconomyLab - 07/12/2023

The city as a living laboratory for a bioeconomic, sustainable economic area

Baden-Württemberg is leading the way in the transition to a climate-neutral and sustainable economy. One of the projects undertaken is the Fraunhofer IGB’s "urban BioEconomyLab" project which aims to develop a transformation model and living laboratory to find bioeconomic solutions for the sustainable design of cities and municipal industry. What is new is that the IGB takes a systemic approach, focusing on biobased and circular value…